Weather will be beautiful and sunny during the day - probably in the 70s and cool and breezy at night.
Whatever you do, you MUST have breakfast at Dotties! It freakin rocks. Neighborhood is not great, but the clientele comes from all over the city just to eat breakfast there. YUMMO!
When we go back up there to visit, we either stay with my old roomie OR stay at our favorite very inexpensive hotel on Lombard Street. Its clean, it has parking, and its super close to Union Street, Chestnut Street, and not far from Fisherman's Wharf and Ghirardhelli Square. Its called the Coventry Inn:
http://www.coventrymotorinn.com/
I lived in SF for 3 years and looooooooooooove it there. Here are some really fun things to do:
RESTAURANTS
Izzy’s Steaks & Chops (on Steiner)
Marina District
http://www.izzyssteaksandchops.com
Beach Chalet
Sunset District
http://www.beachchalet.com
Boulevard
http://www.boulevardrestaurant.com
The Fly Trap
Downtown
http://www.flytraprestaurant.com
Dotties True Blue Café
Downtown
http://www.mrbreakfast.com/r_display.asp?restid=3533
The Stinking Rose
North Beach
http://www.thestinkingrose.com
Hawthorne Lane
South of Market
http://www.hawthornelane.com
The Buena Vista
Marina District
http://www.thebuenavista.com
Osaka
Marina District
http://www.osakaonfillmore.com
HANG-OUTS
North Beach (fantastic eateries and coffee houses)
http://www.sfnorthbeach.org
Union Square
Downtown
http://www.sfgate.com/traveler/guide/sf/neighborhoods/unionsq.shtml
Golden Gate Park
Richmond District
http://www.sfgate.com/traveler/guide/sf/neighborhoods/ggpark.shtml
Haight-Ashbury
http://www.sfgate.com/traveler/guide/sf/neighborhoods/haight.shtml
Vesuvio
North Beach
http://www.vesuvio.com
Union Street
Marina District
http://www.unionstreet.com
Chestnut Street
Marina District
http://www.chestnutshop.com
Fillmore Street
Marina District
http://www.fillmorestreetsf.com
Twin Peaks
http://www.sftravel.com/twinpeakssanfrancisco.html
Pier 39
Marina District
http://www.pier39.com
Japantown
http://www.sfjapantown.org
HOTELS W/ GREAT TOP FLOOR LOUNGES
Grand Hyatt – Union Square
Downtown
http://grandsanfrancisco.hyatt.com/hyatt/hotels/index.jsp
Mariott Hotel – Downtown
http://marriott.com/property/propertypage/SFODT